Tumor Tip of the Week-08-11-2023 Ductal & Lobular Breast Cancer - Omega Healthcare

Tumor Tip of the Week-08-11-2023 Ductal & Lobular Breast Cancer

Tumor Tip header image

Scenario: 2023

Patient diagnosed with single tumor Right UOQ Breast 1.9 cm DCIS & 2mm invasive lobular carcinoma

Question:  How would you code histology?

  • 8520/3 Lobular carcinoma, nos
  • 8522/3 Infiltrating duct and lobular carcinoma

Answer:  8522/3 Infiltrating duct and lobular carcinoma

Rationale:

BREAST SOLID TUMOR RULES

  • Multiple Primary Rules
    • Rule M3 Abstract a single primaryi when there is a single tumor.
      • Note 1: A single tumor is always a single primary.
      • Note 2: The tumor may overlap onto or extend into adjacent/contiguous site or subsites/quadrants.
      • Note 3: The tumor may have in situ and invasive components.
      • Note 4: The tumor may have two or more histologic components.
    • Histology Rules-Code the histology according to the rule that fits the case
      • Different histologies
        • Code the histology which comprises the majority of tumor.
        • Note 1: This instruction does not apply to:
          • Invasive carcinoma NST/ductal and lobular carcinoma (use the combination code 8522/3).
        • Rule H8 Code the invasive histology when both invasive and in situ components are present (see Notes 2 and 3 for exceptions).
          • Note 2: The following histologies are exceptions to this rule. When a single tumor has one of the histologies listed, continue through the rules.
            • Encapsulated papillary carcinoma with invasion/with invasive carcinoma, NST/invasive duct carcinoma
            • Solid papillary carcinoma with invasion
          • Note 3: When a single tumor has carcinoma NST/duct and lobular with different behaviors, continue through the rules. 
  • Rule H15 Code duct carcinoma and lobular carcinoma 8522/3 when the final diagnosis is any of the following:
    • Invasive carcinoma NST/duct carcinoma and invasive lobular carcinoma (includes invasive pleomorphic lobular carcinoma)
    • Intraductal and invasive lobular carcinoma (includes invasive pleomorphic lobular carcinoma)
    • Infiltrating duct and lobular carcinoma in situ (LCIS)
    • Infiltrating duct and pleomorphic lobular carcinoma in situ
    • Infiltrating lobular carcinoma and ductal carcinoma in situ (DCIS)
    • Infiltrating pleomorphic lobular carcinoma and ductal carcinoma in situ (DCIS)
    • Note 1: Assign behavior code /3 even when an in situ histology is mixed with an invasive. This aligns with ICD-O-3.2 and was vetted with specialty matter experts.
    • Note 2: CAP uses the term Invasive carcinoma with ductal and lobular features (“mixed type carcinoma”) as a synonym for duct carcinoma/carcinoma NST AND lobular carcinoma 8522/3.
    • Note 3: Although the instructions in the “Coding Multiple Histologies in a Single Tumor” section state, “Code the histology that comprises the majority of tumor”, 8522/3 identifies both invasive carcinoma NST/duct carcinoma and invasive lobular carcinoma and is the most accurate description.
  • And for those of you who are like, what??? When did that change, be sure to review the December 2022 Revision History for the Solid Tumor Rules
    • Breast: Table 2: Histology Combination Codes
    • Duct + Lobular row
      • 8519 (Pleomorphic lobular carcinoma) added
      • Note 1 deleted: Both histologies, duct and lobular, must have the same behavior code.
      • “Additional Combinations of duct and lobular” section added

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