06-09-2023 Grade for LAMN or HAMN of the Appendix
Scenario 2023:
Question: How would you code the grade for High Grade HAMN?
- 1 G1: Well differentiated
- 2 G2: Moderately differentiated
- 3 G3: Poorly differentiated
- 9 Grade cannot be assessed (GX); Unknown
Answer: 2 G2: Moderately differentiated
Rationale:
- AJCC Cancer Staging System: Appendix: Version 9 of AJCC Cancer Staging System (Version 9 of the AJCC Cancer Staging System) (p. 20). American College of Surgeons. Kindle Edition.
- By WHO grading definitions, a LAMN is histologically graded as G1 or well differentiated.
- By WHO grading definitions, a HAMN is histologically graded as G2 or moderately differentiated.
- CAnswer Forum post
- According to AJCC page 20 of the Appendix Cancer Staging Protocol, by WHO histologic grading definitions, LAMN is G1 or well-differentiated and HAMN is G2 or moderately differentiated.