Tumor Tips

Tumor Tip of the week – 4-12-2024 Multifocal Not the Same as Multiple Synchronous

Scenario: 2024

  • DRE: Multiple areas of nodularity bilateral lobes of the Prostate, No Inguinal Adenopathy, PSA 4.5, Adenocarcinoma Gleason 3+3 in 6/12 cores
  • MRI: 2 lesions (1.1 cm and .8cm) PI-RADS 5
  • Physician Stage cT2c cN0 cM0 Stage IIA

Question:  How would you assign AJCC Clinical T Suffix

  • (m) Multiple synchronous tumors
  • BLANK

Answer:  BLANK

Rationale: 

  • Refer to AJCC 8th Edition
    • Chapter 1 page 27 for the instructions on the use of the (m) suffix
    • Chapter 58 page 725 under Anatomy, Primary Sites

The Clinical stage will be based on the DRE alone but does not include the information from the biopsy or MRI.  The m suffix would only be used if there were multiple synchronous tumors, it would not be used in the prostate for multifocal tumors.  The only time the m suffix is used for multifocal tumors is in the Thyroid (differentiated and anaplastic only).

Multifocal tumors is not the same as Multiple Synchronous tumors.  Refer to the CAnswer Forum for multiple posts on this topic.

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