Tumor Tips

Tumor Tip of the Week 01-16-2026 New Notes for Plasma Cell Myeloma SSDIs

1-16-2026

Scenario:

  • 1-16-2026, patient presents to your facility for treatment. The patient was diagnosed at an outside facility.  The abstractor does not have access to those notes, however, the treating physician at your facility states the patient is here for treatment for a RISS Stage 1 Plasma Cell Myeloma diagnosed 1-5-2026 after a full staging work up at the outside facility. 

Question: How would you assign the SSDI Serum Beta-2 Microglobulin Pretreatment Level?

  • 0 β2-microglobulin < 3.5 mg/LSingle
  • 7 Test ordered, results not in chart
  • 9 Not documented in medical record 

Answer: 0 β2-microglobulin < 3.5 mg/LSingle

SSDI Manual v3.3

Note 3: Component of R-ISS Stage

Serum Beta-2 Microglobulin is part of the Revised International Staging (R-ISS).

Elevated serum microglobulin is defined as 5.5 mg/L

Use the cut points listed in the table below regardless of the lab’s reference range.

Code 0 if physician states RISS Stage 1 and there is no other information

Code 2 if physician states RISS Stage 3 and there is no other information

REVIEW SSDI Change Log 3.3  https://apps.naaccr.org/ssdi/list/?_gl=1*1k9sirh*_ga*MTQ2NzY5OTExLjE3NTE1NDYzNTU.*_ga_V7J8GWYK5P*czE3Njg1ODk5OTIkbzEwMyRnMSR0MTc2ODU5NDI3MyRqNjAkbDAkaDA.

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