Tumor Tips

Tumor Tip of the Week-04-18-2025 Lung-Low Cervical Nodes Distant or Reg-depends on the field

04-18-2025

Scenario:

  • PET: 2.1 cm RUL mass with moderate activity. Malignancy cannot be excluded. Nonspecific 1.2 x 0.7 cm left lower cervical lymph node with mild activity. No hypermetabolic masses are identified in the abdomen or pelvis
  • Ultrasound-guided biopsy of left cervical lymph node: metastatic adenocarcinoma, consistent with lung primary

Question: Are mets to the lower cervical lymph nodes reflected in the cN or cM category?

  • cN
  • cM

Answer: cN- regional lymph node mets

Discussion: Although metastasis to the Ipsilateral or Contralateral Low cervical/Supraclavicular node(s) are considered regional nodes when assigning AJCC Stage and EOD, the Summary Stage manual considers mets to Ipsilateral or Contralateral Low Cervical/Supraclavicular node(s) Distant lymph node mets.

TIP: Be sure to code the field according to the instructions in the appropriate manual for that field.  Do not mix and match instructions from various manuals for other fields.

FieldCodeDefinition
AJCC clinical N CategorycN3AJCC 8th Edition Chapter 36 Lung Refer to Fig. 36.1 & Table 36.1, the same info is also in Version 9 Per IASLC Low cervical nodes are in the Supraclavicular Zone, Lymph node Station 1
EOD Regional Nodes600EOD Manual IPSILATERAL or CONTRALATERAL Low cervical Proximal root Scalene (inferior deep cervical) Sternal notch Supraclavicular (transverse cervical)
EOD Mets00EOD Manual No distant metastasis
Summary Stage7Summary Stage Manual 2018 Distant lymph node(s), NOS         IPSILATERAL or CONTRALATERAL                  Low cervical

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