June 12, 2023

Tumor Tip of the week 06-09-2023 Grade for LAMN or HAMN of the Appendix

06-09-2023 Grade for LAMN or HAMN of the Appendix

Scenario 2023:

  • Pathology report states patient has a High Grade HAMN?

Question: How would you code the grade for High Grade HAMN?

  • 1 G1: Well differentiated
  • 2 G2: Moderately differentiated
  • 3 G3: Poorly differentiated
  • 9 Grade cannot be assessed (GX); Unknown

Answer: 2 G2: Moderately differentiated

Rationale:

  • AJCC Cancer Staging System: Appendix: Version 9 of AJCC Cancer Staging System (Version 9 of the AJCC Cancer Staging System) (p. 20). American College of Surgeons. Kindle Edition.
  • By WHO grading definitions, a LAMN is histologically graded as G1 or well differentiated.
  • By WHO grading definitions, a HAMN is histologically graded as G2 or moderately differentiated.
  • CAnswer Forum post
  • According to AJCC page 20 of the Appendix Cancer Staging Protocol, by WHO histologic grading definitions, LAMN is G1 or well-differentiated and HAMN is G2 or moderately differentiated.

https://cancerbulletin.facs.org/forums/forum/site-specific-data-items-grade-2018/general-instructions/139427-coding-the-grade-when-its-part-of-the-histology#post139441

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